Fig. 6.

RSG abrogated insulin resistance induced by adipocyte raptor deletion. Body weight gain (A); epididymal (B), retroperitoneal (C), and liver (D) masses; ITT (E); and rates of glucose disappearance (kITT) (F); liver PEPCK and G6Pase mRNA levels (G); fasting insulin (H); and adipose tissue mRNA levels of inflammatory proteins (I) in HFD-fed RapWT and RapKO mice treated with RSG (30 mg/kg/day) as admixture in the diet for 8 weeks. Values are mean ± SEM of four to eight mice. Means not sharing a common superscript are significantly different from each other, P < 0.05.