TABLE 1.
L-IS, n = 20 | L-IR, n = 20 | O-IS, n = 20 | O-IR, n = 20 | T2D. n = 12 | P | |
Age (years) | 18.2 ± 1.2 | 17.6 ± 1.6 | 17.9 ± 1.0 | 17.6 ± 1.0 | 18.4 ± 2.9 | 0.52 |
Race, n (% Caucasian) | 6 (30) | 10 (50) | 10 (50) | 10 (50) | 6 (50) | 0.64 |
Weight (kg) | 66.9 ± 5.8c | 69.3 ± 7.5c | 97.4 ± 8.9b | 120.5 ± 22.4a | 118.8 ± 24.6a | <0.001 |
BMI (kg/m2) | 21.9 ± 1.3c | 22.1 ± 1.6c | 30.8 ± 2.9b | 38.0 ± 6.3a | 38.2 ± 6.0a | <0.001 |
Fasting insulin (mU/ml) | 4.5 ± 1.2c | 42.5 ± 16.3b | 8.1 ± 1.9b | 73.2 ± 21.8a | Na | <0.001 |
Fasting glucose (mg/dl) | 70 ± 8b | 82 ± 18b | 80 ± 9b | 81 ± 8b | 176 ± 92a | <0.001 |
2 h OGTT glucose (mg/dl) | NA | NA | 81 ± 18 | 84 ± 20 | NA | 0.628 |
Total cholesterol (mg/dl) | 139 ± 15b | 146 ± 36b | 146 ± 27b | 159 ± 29b | 196 ± 22a | <0.001 |
HDL-C (mg/dl) | 46 ± 6a | 42 ± 12ab | 40 ± 10ab | 35 ± 8b | 42 ± 8a | 0.020 |
LDL-C (mg/dl) | 79 ± 13b | 74 ± 29b | 92 ± 24b | 98 ± 25b | 125 ± 29a | <0.001 |
TGs (mg/dl) | 67 ± 20b | 159 ± 171ab | 69 ± 32b | 136 ± 81ab | 222 ± 136a | <0.001 |
Data are presented as mean ± SD or number (%). NA indicates value was not obtained. P values are from ANOVA for a five-group comparison, except insulin where four-group ANOVA was used and 2 h oral glucose tolerance test (OGTT) where unpaired t-test was used. If the ANOVA was significant, between-group differences were tested and are marked by superscripts. Superscripts marked “a” indicate values are significant different from “b” or “c” at P < 0.05. Those marked as “ab” are not different from “a” and not different from “b.”