Fig. 6.
Cerebrovascular leakiness and vessel coverage in 8-month-old EFAD mice. Fibrinogen (red) levels in the CX (A) and SB (B) follow the order: ♀ E4FAD > ♀ E3FAD = ♂ E4FAD > ♂ E3FAD. Green = CD31; n = 8. Data expressed as mean ± SEM. *P < 0.05 by two-way ANOVA and Tukey’s post hoc comparisons. #P < 0.05 by two-way AVOVA followed Fisher’s LSD test (new data). C: Laminin (green) staining as a marker of total vessel coverage follows the order: ♂ E3FAD > ♂ E4FAD ≥ ♀ E3FAD > ♀ E4FAD in the deep CX and SB [adapted from (71)].