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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Ocul Surf. 2016 Feb 2;14(2):189–195. doi: 10.1016/j.jtos.2015.10.004

Figure 1.

Figure 1

Hyperosmolar stress to the ocular surface causes the release of MMP-9-TIMP complexes from neutrophils, which when released from bound inactivating TIMP disrupt corneal surface epithelial junctions.