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. 2017 Jul 6;8(32):52026–52044. doi: 10.18632/oncotarget.19036

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Copyright: © 2017 Weisberg et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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A.-B. Three-day treatment of normal PBMCs (A) with midostaurin+/−R406. MOLM14 cells (B) were treated in parallel as a positive control for drug effectiveness. C.-E. Three-day treatment of mutant FLT3-positive AML primagrafts with midostaurin+/−R406 (C) and midostaurin+/−PRT062607 (D-E). F. SYK protein expression in normal PBMC cells and FLT3-ITD-positive AML primagraft cells.