Table 1B. IC50s (nM) (mean+/−S.D.), generated using GraphPad Prism 7 Software, for crenolanib and AC220 tested against Ba/F3-FLT3-ITD and Ba/F3-FLT3-ITD+SYK-TEL. Cell growth assays were carried out for approximately 3 days.
crenolanib (IC50, nM) |
quizartinib (IC50, nM) |
|
---|---|---|
Ba/F3-FLT3-ITD | 6.2+/−2 | 0.3+/−0.3 |
Ba/F3-FLT3-ITD+SYK-TEL | 520.6+/−121.1 | 627.5+/−32.2 |