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A.-D. Intrapatient changes of the numbers of copies/μL of ESR1 and PIK3CA mutations under treatment with each representative therapeutic drug in 21 patients with longitudinal data. A. Patients treated with AIs, B. Patients treated with SERDs, C. Patients treated with SERMs, D. Patients treated with EE2. Abbreviations; AI, aromatase inhibitor; SERD, selective estrogen receptor downregulator; SERM, selective estrogen receptor modulator; EE2, ethinyl estradiol.
