Table 2. Multivariate cox proportional-hazards analysis in 105 patients with ER-positive breast cancer.
| Variable | Multivariate Analysis | ||
|---|---|---|---|
| Hazard Ratio | 95% confidence interval | P Value | |
| Age at surgery <=53yrs(VS.>53yrs) | 1.478 | 0.612-3.568 | 0.385 |
| Histological grade | |||
| G1 | 0.053 | 0.009-0.292 | 0.001 |
| G2 | 0.181 | 0.064-0.513 | 0.001 |
| G3 | 1 | 1 | |
| Tumor size <=5cm(VS.>5cm) | 7.443 | 1.754-31.582 | 0.006 |
| Lymph node metastasis Negative (VS. Positive) | 0.349 | 0.091-1.340 | 0.125 |
| AJCC | |||
| 1 | 0.217 | 0.028-1.688 | 0.144 |
| 2 | 0.207 | 0.060-0.718 | 0.013 |
| 3 | 1 | 1 | |
| HER2 expression Negative (VS. Positive) | 0.742 | 0.216-2.551 | 0.636 |
| Beclin 1 expression Low (VS.High) | 4.795 | 1.603-14.341 | 0.005 |