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. 2016 Aug 4;8(32):52178–52192. doi: 10.18632/oncotarget.11052

Figure 3. HCV mice are hypersensitive to ConA-induced hepatic injury.

Figure 3

A. A representative photograph of the macroscopic evaluation of livers at 24 h after ConA injection (10 μg/g body weight). B. A time course study of serum ALT levels at 0, 6 and 24 h post-ConA injection. The results shown represent one of three independent experiments. *P<0.05. C. Photomicrographs of H/E-stained liver sections and D. statistical analyses of the percentage of positive TUNEL-stained hepatocytes obtained from HCV and control mice at 24 h after challenge with ConA (magnification: 100×, the arrow indicates parenchymal loss). E. The mice were treated with a high dose of ConA (20 μg/g body weight), and the survival rates of the mice were observed after ConA injection.