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. 2017 Apr 10;8(32):52345–52356. doi: 10.18632/oncotarget.17017

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Copyright: © 2017 Kim et al.

This article is distributed under the terms of the Creative Commons Attribution License (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.

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(A) Aldi-6 structure is shown (3-(Dimethylamino)-4′-bromopropiophenone, MW 261). (B) Common core structure of phenyl-vinyl-ketone in Aldis-1, 2, 3 and 6 is shown. (C) IC₅₀ values of ALDH were determined by an activity assay with purified ALDH1A1, 2 and 3A1 isozymes with Aldi-6 (1–100,000 nM).