. 2017 May 5;8(32):52923–52934. doi: 10.18632/oncotarget.17629

Table 2. Comparisons of PWMT and TWL among the wortmannin-positive control, DMSO and wortmannin groups on the 1^st day before drug administration and also on the 3^rd, 7^th and 14^th day after drug administration.

	Group	1^st day before drug administration	After drug administration
	Group	1^st day before drug administration	3^rd day	7^th day	14^th day
PWMT (g)	Wortmannin positive-control group	37.02 ± 3.53	36.32 ± 3.40	35.55 ± 4.30	35.06 ± 4.21
	DMSO group	38.20 ± 5.90	30.90 ± 3.60^*▲	23.22 ±3.50^*▲#	15.4 ± 3.80^*▲#&
	Wortmannin group	36.78 ± 4.45	35.95 ± 3.65	36.28 ± 4.02	35.83 ± 3.23
TWL (s)	Wortmannin positive-control group	11.85 ± 1.70	11.78 ± 1.55	10.84 ± 1.18	11.15 ± 1.19
	DMSO group	11.65 ± 1.47	9.06 ± 1.08^*▲	7.59 ± 0.82^*▲#	5.53 ± 1.39^*▲#&
	Wortmannin group	12.05 ± 1.60	12.50 ±0.89	11.55 ± 0.94	11.92 ± 1.21

Note: PWMT, paw withdrawal mechanical threshold; TWL, thermal withdrawal latency; DMSO, dimethyl sulfoxide; *, P < 0.05 in comparison with the wortmannin positive-control group; ^#, P < 0.05 in comparison with the present group on the 1^st day before drug administration; ^▲, P < 0.05 in comparison with the present group on the 3^rd day after drug administration; ^&, P < 0.05 in comparison with the present group on the 7^th day after drug administration.

Table 2. Comparisons of PWMT and TWL among the wortmannin-positive control, DMSO and wortmannin groups on the 1st day before drug administration and also on the 3rd, 7th and 14th day after drug administration.

Table 2. Comparisons of PWMT and TWL among the wortmannin-positive control, DMSO and wortmannin groups on the 1^st day before drug administration and also on the 3^rd, 7^th and 14^th day after drug administration.