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. 2017 May 8;8(32):52983–52994. doi: 10.18632/oncotarget.17677

Figure 1. Expression levels of miR-133b and ABCC1 in normal and drug-resistant CRC cell lines.

Figure 1

(A) The expression of miR-133b was decreased in CRC drug-resistant cell lines HCT-8/5-FU and HCT-8/VCR compared with that of normal CRC cell HCT-8, as detected by RT-qPCR. (B) Increased expression level of ABCC1 was detected in HCT-8/5-FU and HCT-8/VCR compared with that of HCT-8, as detected by RT-qPCR. (C) The expression level of ABCC1 was detected by Western blot analysis, and was increased in HCT-8/5-FU and HCT-8/VCR. The data are expressed as the mean ± standard deviation. The results are representative of three independent experiments. *P<0.05.