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(A) BxPC3, PANC1 and 779e cells were treated with vehicle or pitavastatin (2 μM, 5 μM and 10 μM) 24 hours after plating. Replicate plates were counted at 72 and 96 or 120 hours after plating, revealing dose responsive growth inhibition. (B) Pitavastatin induced cytoskeletal alterations are evident in cells treated with 10 μM pitavastatin for 48hr. Bright field images are 100X original. Data are represented as mean +/−SD.
