Table 2. Candidate target genes regulated by miR-217.
Entrez gene | Gene symbol | Gene name | Conserved sites | GEO data | *TCGA_OncoLnc | |||
---|---|---|---|---|---|---|---|---|
8mer sites | 7mer-m8 sites | 7mer-A1 sites | Total | FC(log2) | P-value | |||
9644 | SH3PXD2A | SH3 and PX domains 2A | 1 | 1 | 1 | 3 | 1.631 | 0.3620 |
54443 | ANLN | anillin, actin binding protein | 1 | 1 | 0 | 2 | 1.729 | 0.0014 |
3624 | INHBA | inhibin, beta A | 0 | 1 | 0 | 1 | 5.190 | 0.0414 |
1295 | COL8A1 | collagen, type VIII, alpha 1 | 1 | 0 | 0 | 1 | 4.623 | 0.3640 |
2335 | FN1 | fibronectin 1 | 0 | 1 | 0 | 1 | 3.727 | 0.0950 |
860 | RUNX2 | runt-related transcription factor 2 | 1 | 0 | 0 | 1 | 2.932 | 0.4790 |
10085 | EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 1 | 0 | 0 | 1 | 2.560 | 0.5300 |
6400 | SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 1 | 0 | 0 | 1 | 2.375 | 0.0950 |
22943 | DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0 | 0 | 1 | 1 | 2.303 | 0.0110 |
800 | CALD1 | caldesmon 1 | 0 | 0 | 1 | 1 | 2.067 | 0.5440 |
10630 | PDPN | podoplanin | 0 | 1 | 0 | 1 | 1.957 | 0.3500 |
79070 | KDELC1 | KDEL (Lys-Asp-Glu-Leu) containing 1 | 1 | 0 | 0 | 1 | 1.870 | 0.0969 |
55454 | CSGALNACT2 | chondroitin sulfateN-acetylgalactosaminyltransferase 2 | 0 | 1 | 0 | 1 | 1.781 | 0.6930 |
57181 | SLC39A10 | solute carrier family 39 (zinc transporter),member 10 | 0 | 1 | 0 | 1 | 1.770 | 0.0007 |
6091 | ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0 | 0 | 1 | 1 | 1.769 | 0.8790 |
22856 | CHSY1 | chondroitin sulfate synthase 1 | 0 | 0 | 1 | 1 | 1.652 | 0.3330 |
23603 | CORO1C | coronin, actin binding protein, 1C | 0 | 0 | 1 | 1 | 1.566 | 0.0056 |
50515 | CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 1 | 0 | 0 | 1 | 1.559 | 0.0024 |
9444 | QKI | QKI, KH domain containing, RNA binding | 0 | 0 | 1 | 1 | 1.554 | 0.9170 |
* Kaplan-Meier analysis log-rank P-value < 0.05
Poor prognosis with a high expression