Table 5. Single loci associations with high altitude polycythemia risk in Han subjects.
SNP_ID | Model | Ref Allele | Alt Allele | OR | 95% CI | p value |
---|---|---|---|---|---|---|
rs2291805 | Dominant | 0.318 | 0.118-0.859 | 0.024 | ||
Recessive | C | T | 0.245 | 0.095-0.629 | 0.999 | |
Additive | 0.308 | 0.121-0.784 | 0.014 | |||
rs3754334 | Dominant | 0.385 | 0.151-0.982 | 0.046 | ||
Recessive | G | A | 0.436 | 0.140-0.857 | 0.999 | |
Additive | 0.361 | 0.148-0.878 | 0.025 | |||
rs13375644 | Dominant | 0.316 | 0.109-0.915 | 0.034 | ||
Recessive | C | T | 0.452 | 0.102-0.779 | 0.999 | |
Additive | 0.303 | 0.113-0.818 | 0.018 | |||
rs699 | Dominant | 0.360 | 0.142-0.917 | 0.032 | ||
Recessive | G | A | 0.524 | 0.027-10.32 | 0.671 | |
Additive | 0.403 | 0.171-0.952 | 0.038 | |||
rs3789679 | Dominant | 2.683 | 1.022-7.043 | 0.045 | ||
Recessive | G | A | 1.869 | 0.329-10.6 | 0.480 | |
Additive | 2.088 | 0.956-4.561 | 0.065 | |||
rs4762 | Dominant | 0.248 | 0.074-0.826 | 0.023 | ||
Recessive | G | A | 0.25 | 0.015-4.249 | 0.338 | |
Additive | 0.331 | 0.122-0.898 | 0.030 | |||
rs5051 | Dominant | 0.36 | 0.141-0.916 | 0.032 | ||
Recessive | T | C | 0.182 | 0.014-2.316 | 0.189 | |
Additive | 0.377 | 0.165-0.862 | 0.021 |
OR: odds ratio; 95% CI: 95% confidence interval; p<0.05 indicates statistical significance for genetic model.