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MDA-MB-231 or MCF-7 cells were co-cultured in the presence of Cystatin C at 0–100 ng/ml of varying concentrations. (A) The CTSB levels in MDA-MB-231 cells. (B) The activity of CTSB in MDA-MB-231 cells. (C) The CTSB levels in MCF-7 cells. (D) The activity of CTSB in MCF-7 cells. (a) p <0.05, (b) p <0.01, when comparing to basal. Data (mean ±standard error) representative results derived from a minimum of 3 independent experiments.
