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. 2017 Jun 22;8(32):53531–53541. doi: 10.18632/oncotarget.18602

Table 3. Comparison of compliance in the individual items of ERAS protocol.

Total I [0, 60%) II [60%, 70%) III [70%, 80%) IV [80%, 100%] P value
Patients (n) 254 66 63 53 72
Education and counselling 254 (100%) 66 (100%) 63 (100%) 53 (100%) 72 (100%)
Nutritional assessment and support 119 (46.9%) 20 (30.3%) 26 (41.3%) 26 (49.1%) 47 (65.3%) < 0.001
Cardiopulmonary function evaluation 214 (84.3%) 39 (59.1%) 54 (85.7%) 49 (92.5%) 72 (100%) < 0.001
No bowel preparation 35 (13.8%) 4 (6.1%) 4 (6.3%) 7 (13.2%) 20 (27.8%) < 0.001
Forbidden to drink and eat 207 (81.5%) 40 (60.6%) 52 (82.5%) 46 (86.8%) 69 (95.8%) < 0.001
Carbohydrate drinks 154 (60.5%) 15 (22.7%) 29 (46.0%) 42 (79.2%) 68 (94.4%) < 0.001
Antibiotics prophylaxis 254 (100%) 66 (100%) 63 (100%) 53 (100%) 72 (100%)
No premedication 231 (90.9%) 53 (80.3%) 59 (93.7%) 51 (96.2%) 68 (94.4%) 0.013*
Anesthesia protocols 150 (59.1%) 23 (34.8%) 35 (55.6%) 32 (60.4%) 60 (83.3%) < 0.001
Laparoscopic surgery 198 (78.0%) 43 (65.2%) 48 (76.2%) 42 (79.2%) 65 (90.3%) 0.005
Depth of anesthesia 229 (90.2%) 52 (100%) 58 (100%) 51 (100%) 68 (100%) 0.004
Ventilation management 225 (88.6%) 46 (69.7%) 59 (93.7%) 50 (94.3%) 70 (97.2%) < 0.001
Muscle relaxant 109 (42.9%) 14 (21.2%) 22 (34.9%) 28 (52.8%) 45 (62.5%) < 0.001
Active warming 200 (78.7%) 43 (65.2%) 44 (69.8%) 45 (84.9%) 68 (94.4%) < 0.001
Perioperative fluid management 126 (49.6%) 15 (22.7%) 28 (44.4%) 33 (62.3%) 50 (69.4%) < 0.001
Control blood glucose 210 (82.7%) 41 (62.1%) 53 (84.1%) 47 (88.7%) 69 (95.8%) < 0.001
PONV prophylaxis 223 (87.8%) 46 (69.7%) 57 (90.5%) 49 (92.5%) 71 (98.6%) < 0.001
Thrombo-prophylaxis 218 (85.8%) 45 (68.2%) 55 (87.3%) 49 (92.5%) 69 (95.8%) < 0.001
No nasogastric tube 237 (93.3%) 60 (90.9%) 58 (92.1%) 48 (90.6%) 71 (98.6%) 0.127*
Prevention of stress ulcer 233 (91.7%) 58 (87.9%) 57 (90.5%) 48 (90.6%) 70 (97.2%) 0.170*
Multimodal analgesic approaches 132 (52.0%) 15 (22.7%) 25 (39.7%) 33 (62.3%) 59 (81.9%) < 0.001
Incision management 226 (89.0%) 49 (74.2%) 56 (88.9%) 50 (94.3%) 71 (98.6%) < 0.001
Early oral intake 113 (44.5%) 16 (24.2%) 17 (27.0%) 25 (47.2%) 55 (76.4%) < 0.001
Early mobilisation 119 (46.9%) 12 (18.2%) 19 (30.2%) 28 (52.8%) 60 (83.3%) < 0.001
Remove drainage tubes 92 (36.2%) 6 (9.1%) 10 (15.9%) 23 (43.4%) 53 (73.6%) < 0.001
Remove urinary catheter 41 (16.1%) 1 (1.5%) 3 (4.8%) 12 (22.6%) 25 (34.7%) < 0.001

*Fisher exact test, all other statistics: Chi-Square test.