Table 1. Association analysis between clinical parameters and EMT-related gene sets by GSEA.
EMT up-regulated | EMT down-regulated | |||||
---|---|---|---|---|---|---|
Phenotypes1 | NES | NOM p-val | FWER p-val2 | NES | NOM p-val | FWER p-val |
Gender(Male vs Female) | −1.223 | 0.17 | 0.209 | −1.133 | 0.247 | 0.348 |
Age(≥ 60 ys vs < 60 ys) | 1.059 | 0.35 | 0.432 | −1.128 | 0.258 | 0.331 |
Smoking(≥ 20 pys vs < 20 pys) | −1.196 | 0.198 | 0.231 | −0.949 | 0.549 | 0.609 |
T(T3&T4 vs T1&T2) | 1.054 | 0.394 | 0.448 | 0.729 | 0.94 | 0.949 |
N(N1&N2 vs N0) | 1.705 | <0.001 | <0.001*** | 0.95 | 0.552 | 0.612 |
TNM Stage(I&II vs III) | 1.386 | 0.068 | 0.08* | 0.664 | 0.975 | 0.976 |
Differ.(P vs M&W) | 0.928 | 0.539 | 0.648 | −1.246 | 0.142 | 0.2 |
1 ys, years; pys, package years; Differ., tumor differentiation grade; P, Poor; M, Moderate; W, Well. 2 *, FWER p value < 0.1; ***, FWER p value < 0.001.