Fig. 4.

Focal male body composition (total body mass, lean mass, and fat mass), adjusted for age. 3 weeks of age corresponds to weaning and 10 weeks of age represents measurements when mice were first granted adult wheel access (though this ranged from 9-10 weeks old), and 11 weeks represents measurements after 6 days of wheel access. Age at approximately 11.5 weeks represents measurements at sacrifice. Each point represents a LSM for ∼25 males and error bars are standard errors. Open points and dashed lines indicate maternal standard diet, filled in points and solid bars indicate maternal Western diet, control mice are in grey, and high-runner mice are in black. 2-tailed P < 0.05 for effect of maternal diet at the time points indicated by an asterisk (*).