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IC50 values of compounds identified in primary screen and tested for concentration dependent inhibition.
| Compound | IC50 (μM) |
|---|---|
| LIPASE INHIBITORS | |
| Ebelactone B (n = 2) | 4.3 |
| ANTI-DEPRESSANTS | |
| Vivactil | 10 |
| Fluoxetine | 10.5 |
| Aventyl | 14.5 |
| Duloxetine | 16 |
| Norcyclobenzaprine | 16 |
| Maprotiline | 16 |
| Desiprimine | 16.5 |
| Lofepramine | 21 |
| Sertraline | 23.5 |
| OTHER | |
| Perhexiline Maleate | 4.7 |
| Febuxostat | 8 |
| Alfuzosin | 11 |
| Stattic | 12.5 |
| Fendiline | 13 |
| Tomoxetine | 14.5 |
| Indatraline | 27 |
