Table 3.
Differences in monitored parameters at days 0–3, 5, and 10 post-SAH in patients with good (GO-SAH) and poor (PO-SAH) treatment outcome.
| Monitored parameter | Days 0–3 post-SAH |
Day 5 post-SAH |
Day 10 post-SAH |
||||||
|---|---|---|---|---|---|---|---|---|---|
| GO-SAH | PO-SAH | GO-SAH vs PO-SAH. p value | GO-SAH | PO-SAH | GO-SAH vs PO-SAH. p value | GO-SAH | PO-SAH | GO-SAH vs PO-SAH. p value | |
| C-reactive protein (mg/L) | 125.00 | 130.00 | 0.715 | 50.70 | 115.80 | 0.020 | 22.40 | 109.70 | 0.139 |
| White blood cell count (106/mm3) | 9.86 | 17.47 | <0.001 | 10.57 | 15.03 | 0.044 | 9.66 | 16.84 | 0.445 |
| Haemoglobin (g/dL) | 12.10 | 13.10 | 0.212 | 11.30 | 10.90 | 0.262 | 10.60 | 11.50 | 0.672 |
| Temperature (°C) | 37.00 | 37.00 | 0.736 | 37.40 | 37.20 | 0.273 | 36.90 | 35.70 | 0.512 |
| Fibrinogen (mg/dL) | 485.00 | 550.00 | 0.879 | 509.00 | 676.00 | 0.257 | 428.00 | 698.00 | 0.014 |
| O-phosphoethanolamine (μM) | 4.10 | 6.80 | 0.161 | 4.90 | 7.70 | 0.161 | 5.95 | 8.50 | 0.019 |
| Taurine (μM) | 13.10 | 19.40 | 0.038 | 14.60 | 13.40 | 0.514 | 12.20 | 7.35 | 0.138 |
| Asparagine (μM) | 9.00 | 11.50 | 0.256 | 30.20 | 12.50 | 0.397 | 22.90 | 20.45 | 0.423 |
| Serine (μM) | 45.10 | 76.50 | 0.161 | 77.00 | 61.40 | 0.947 | 79.50 | 94.75 | 0.503 |
| Glycine (μM) | 29.60 | 41.00 | 0.182 | 30.00 | 43.00 | 0.204 | 35.20 | 35.65 | 0.671 |
| Hydroxyproline (μM) | 0.70 | 1.30 | 0.066 | 1.70 | 0.80 | 0.518 | 1.35 | 1.10 | 0.793 |
| Ethylaminev (μM) | 5.80 | 15.80 | 0.102 | 7.90 | 12.10 | 0.134 | 8.85 | 14.50 | 0.35 |
| Glutamine (μM) | 489.90 | 602.50 | 0.182 | 837.30 | 505.10 | 0.585 | 852.50 | 715.60 | 0.483 |
| Aspartic acid (μM) | 0.80 | 2.20 | 0.038 | 0.40 | 1.00 | 0.071 | 0.95 | 1.30 | 0.551 |
| Citruline (μM) | 1.90 | 5.90 | 0.035 | 2.50 | 3.10 | 0.396 | 3.30 | 3.30 | 1 |
| Threonine (μM) | 25.90 | 50.00 | 0.35 | 86.30 | 34.20 | 0.327 | 63.40 | 57.95 | 0.298 |
| Beta-alanine (μM) | 28.30 | 22.00 | 0.07 | 30.00 | 28.60 | 0.497 | 26.85 | 27.85 | 0.893 |
| Alanine (μM) | 70.70 | 138.10 | 0.109 | 115.50 | 113.60 | 0.447 | 120.30 | 141.70 | 0.954 |
| Glutamic acid (μM) | 3.40 | 9.30 | 0.038 | 2.70 | 5.80 | 0.024 | 2.00 | 17.10 | 0.269 |
| Histidine (μM) | 18.90 | 38.10 | 0.256 | 63.60 | 23.70 | 0.711 | 43.55 | 37.45 | 0.753 |
| 3-Methylhistidine (μM) | 0.70 | 1.50 | <0.01 | 1.80 | 1.20 | 0.958 | 1.35 | 1.05 | 0.733 |
| 2-Aminoadipic acid (μM) | 1.30 | 1.70 | 0.076 | 1.50 | 4.10 | 0.071 | 1.30 | 2.45 | 0.033 |
| Gamma-aminobutyric acid (μM) | 0.30 | 0.90 | 0.043 | 0.30 | 0.30 | 0.932 | 0.35 | 0.15 | 0.266 |
| 3-Aminoisobutyric acid (μM) | 0.20 | 0.40 | 0.066 | 0.30 | 0.30 | 0.958 | 0.35 | 0.45 | 0.93 |
| 2-Aminobutyric acid | 4.60 | 8.20 | 0.088 | 11.40 | 5.50 | 0.542 | 10.75 | 6.50 | 0.124 |
| Arginine (μM) | 18.50 | 22.30 | 0.182 | 30.90 | 26.00 | 0.525 | 24.35 | 20.45 | 0.21 |
| Proline (μM) | 4.50 | 14.80 | 0.204 | 18.70 | 10.90 | 0.672 | 16.15 | 18.40 | 0.759 |
| Ornithine (μM) | 7.60 | 27.50 | 0.033 | 17.30 | 28.30 | 0.09 | 17.35 | 33.05 | 0.552 |
| Cystathionine (μM) | 0.80 | 2.80 | <0.01 | 1.00 | 1.80 | 0.089 | 1.30 | 1.50 | 0.199 |
| Cysteine (μM) | 1.60 | 2.30 | 0.141 | 1.50 | 2.20 | 0.243 | 1.95 | 1.40 | 0.329 |
| Lysine (μM) | 43.00 | 74.50 | 0.095 | 87.10 | 55.90 | 0.341 | 72.40 | 72.60 | 0.612 |
| Methionine (μM) | 4.60 | 12.30 | 0.204 | 16.20 | 7.70 | 0.491 | 13.65 | 13.70 | 0.687 |
| Valine (μM) | 31.80 | 62.40 | 0.109 | 102.50 | 33.60 | 0.397 | 87.75 | 72.20 | 0.377 |
| Tyrosine (μM) | 23.00 | 32.50 | 0.083 | 36.60 | 35.80 | 0.876 | 38.60 | 37.30 | 0.676 |
| Isoleucine (μM) | 6.00 | 13.00 | 0.045 | 17.60 | 11.80 | 0.597 | 15.05 | 13.70 | 0.45 |
| Leucine (μM) | 22.90 | 39.70 | 0.109 | 80.30 | 29.80 | 0.397 | 60.95 | 50.55 | 0.532 |
| Phenylalanine (μM) | 21.20 | 38.80 | 0.062 | 51.30 | 32.40 | 0.665 | 45.40 | 44.45 | 0.913 |
| Tryptophan (μM) | 8.00 | 12.20 | 0.066 | 13.60 | 13.60 | 0.606 | 12.60 | 13.55 | 0.804 |
Median levels of the amino acids are presented in the table. p values were calculated either by Mann–Whitney or Student’s t-test. Significant differences are shown in bold.