Table 1.
Thymic cell subsets in SIRT2+/+ and SIRT2−/− mice.
| Cell subset | SIRT2+/+ | SIRT2−/− |
|---|---|---|
| CD4+ CD8+ | 82.3 ± 3.1 | 82.9 ± 0.4 |
| CD4− CD8− | 2.0 ± 0.6 | 1.8 ± 0.2 |
| CD25+ CD44+ | 1.8 ± 0.6 | 1.6 ± 0.5 |
| CD25− CD44+ | 0.2 ± 0.01 | 0.2 ± 0.01 |
| CD25+ CD44− | 1.4 ± 0.6 | 1.3 ± 0.4 |
| CD25− CD44− | 96.6 ± 1.2 | 96.9 ± 1.0 |
| CD4+ CD8− | 12.0 ± 2.3 | 12.1 ± 0.7 |
| CD4− CD8+ | 3.6 ± 0.3 | 3.3 ± 0.8 |
Data are means ± SD of four animals per group expressed as the percentage of total cells (CD4+ CD8+, CD4− CD8−, CD4+ CD8−, and CD4− CD8+) or percentage of CD4− CD8− parental cells (CD25+ CD44+, CD25− CD44+, CD25+ CD44− and CD25− CD44−). Total cell numbers were 49.2 ± 15.4 and 55.2 ± 5.7 millions per thymus in SIRT2+/+ and SIRT2−/− mice, respectively. No statistically significant differences in subset percentages or absolute numbers were detected.