Table 5.

Stenotrophomonas maltophilia trends in susceptibility (MIC values) to nine antibiotics over time.

STb or ST_patient (n)	Antibioticsa
	TZP	LVX	AK	SXT	MIN	TIM	CHL	CIP	CAZ
ST5 (20)	0.046 (0.358)	0.253 (0.023)	0.294 (0.013)	0.437 (0.001)	0.082 (0.22)	0.338 (0.008)	0.073 (0.248)	0.097 (0.18)	0.013 (0.622)
ST91 (11)	0.086 (0.408)	0.199 (0.195)	0.143 (0.28)	0.185 (0.214)	0.187 (0.211)	0.448 (0.034)	0.316 (0.09)	0.207 (0.185)	0.483 (0.025)
ST179 (7)	NDc	0.418 (0.116)	ND	0.391 (0.132)	0.271 (0.23)	ND	0.272 (0.229)	0.367 (0.149)	ND
ST184 (15)	0.003 (0.828)	0.101 (0.246)	0.406 (0.01)	0.004 (0.805)	0.059 (0.382)	0.003 (0.828)	0.028 (0.548)	0.222 (0.075)	0.003 (0.828)
ST185 (8)	0.013 (0.783)	0.031 (0.673)	ND	0.263 (0.193)	0.284 (0.173)	0.034 (0.661)	0.776 (0.003)	0.603 (0.023)	ND
CV_5 (7)	ND	0.406 (0.123)	0.587 (0.044)	0.404 (0.124)	0.263 (0.238)	ND	0.722 (0.015)	0.371 (0.146)	ND
GC_91 (10)	0.713 (0.004)	0.169 (0.27)	0.089 (0.433)	0.104 (0.395)	0.131 (0.337)	0.629 (0.01)	0.2 (0.226)	0.246 (0.174)	0.722 (0.003)
ZC_179 (7)	ND	0.418 (0.116)	ND	0.391 (0.132)	0.271 (0.23)	ND	0.272 (0.229)	0.367 (0.149)	ND
TG_184 (14)	ND	0.103 (0.284)	0.425 (0.011)	0.077 (0.336)	0.112 (0.24)	ND	0.027 (0.57)	0.219 (0.09)	ND
FMa_185 (8)	0.013 (0.783)	0.031 (0.673)	ND	0.263 (0.193)	0.284 (0.173)	0.034 (0.661)	0.776 (0.003)	0.603 (0.023)	ND

The statistical significance of a trend was assessed by linear regression analysis. r² values, along with associated two-tailed p-values (in brackets), are shown. Significant (p < 0.05) values are in bold: red (increasing trend) or blue (decreasing trend).

^aTZP, piperacillin/tazobactam; LVX, levofloxacin; AMK, amikacin; SXT, trimethoprim/sulfamethoxazole; MIN, minocycline; TIM, ticarcillin/clavulanic acid; CHL, chloramphenicol; CIP, ciprofloxacin; CAZ, ceftazidime.

^bST, sequence type.

^cND, not determined: virulence score of ST185 isolates was always null.