Table 3.

Contribution (coefficients) of disease characteristics to behavioral changes.

	FrSBe self-ratings				FrSBe family ratings
	Apathy	Disinhibition	Executive dysfunction	Total score	Apathy	Disinhibition	Executive dysfunction	Total score
Age	0.11	−0.065	0.18	0.17	0.05	−0.25	−0.06	−0.04
Female vs. male	6.97	7.84†	5.81	7.78*	5.77	3.65	5.11	4.8
Education duration (years)	−0.14	0.82	0.32	0.48	−0.8	0.08	0.155	−0.16
Disease duration (years)	−0.34	−0.03	−0.25	−0.205	0.6	0.77†	0.3	0.62*
Examination duration (minutes)	0.47	−4.96*	−0.39	−2.0	1.04	1.84	−0.26	0.35
MS type
CIS vs. RRMS	−7.79	−0.465	−5.095	−5.71	5.97	11.51	1.695	6.15
SPMS vs. RRMS	3.03	−0.94	−2.68	1.355	9.46	−0.465	−4.9	4.78
PPMS vs. RRMS	−7.25	9.775	−7.32	−3.07	24.15†	30.88†	2.85	24.36*
EDSS	2.72	2.88†	2.79	2.7	0.23	1.11	2.71	1.11
Not treated vs. treated	3.97	0.62	2.08	2.26	−6.94	−13.42†	−0.3	−6.72

*p < 0.05.

^†p < 0.01.

EDSS, Expanded Disability Status Scale; CIS, clinically isolated syndrome; RRMS, relapsing-remitting multiple sclerosis; SPMS, secondary progressive multiple sclerosis; PPMS, primary progressive multiple sclerosis; FrSBe, Frontal Systems Behavior Scale.