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. 2017 Sep 2;18:165. doi: 10.1186/s12931-017-0651-5

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Stimulatory effects of ARDS patient’s BALF on human monocytic cells. It showed that 6 histone-related cytokines were all notably increased in the supernatant of ARDS BALF-treated human monocytic U937 cells, whereas addition of anti-histone H4 antibody or heparin could decrease these cytokine levels (all p < 0.05). Variables were expressed as mean ± standard deviation (SD)