Table 4.

Regression analyses with change in Larsen score between baseline and 12 months as dependent variable

	Simple regression			Multiple regression
Variable	Adjusted R-square	β-coeff	p value	Adjusted R-square	β-coeff	p value
DXR decrease (mg/cm2/month)a	0.049	−0.235	0.002	0.069	−0.181	0.033
DAS28b	0.015	0.148	0.070		0.028	0.767
Larsen scoreb	0.017	0.153	0.049		0.068	0.404
Ageb	0.001	0.082	0.291
Gender	0.007	0.114	0.143		0.071	0.381
anti-CCP2 statusb	0.010	−0.125	0.107		−0.128	0.114
RFb	−0.001	−0.069	0.385
Corticosteroid treatment	−0.002	0.042	0.417
Disease duration (months)b	−0.006	0.026	0.739
CRP (mg/L)b	−0.004	0.045	0.566
ESR (mm/h)b	0.024	0.173	0.025		0.133	0.165
DAS28 > 2.6 at 3 months	−0.002	0.065	0.422

Abbreviations: DXR digital X-ray radiogrammetry, DAS28 Disease Activity Score in 28 joints, CCP cyclic citrullinated peptides, RF rheumatoid factor, CRP C-reactive protein, ESR erythrocyte sedimentation rate, BMD bone mineral density

^aDecrease in DXR-BMD between baseline and 3 months

^bBaseline value