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. 2017 Sep 2;16:94. doi: 10.1186/s12940-017-0287-4

Table 4.

Carcinogenicity classifications of chemical exposures found in cigarette smoke

Chemical IARC NTP
Tobacco smoking: Active and passive K
Polycyclic aromatic hydrocarbons (PAHs) RA
Polonium-210
Benzene 1 K
Vinyl chloride 1 K
1,3-butadiene 1 K
Nitrosamine ketone (NNK)

International Agency for Research on Cancer (IARC) classifications: 1 = Carcinogenic to humans, 2A = Probably carcinogenic to humans, 2B = Possibly carcinogenic to humans, 3 = Not classifiable as to its carcinogenicity to humans; U.S. National Toxicology Program (NTP) classifications: K = Known to be a human carcinogen, RA = Reasonably anticipated to be a human carcinogen. Source of exposure list contains most common exposure sources