Table 3.
Right ventricular regional (segmental) strain values stratified by diagnostic groupd
| Overt ARVD/C (N = 39) | Preclinical ARVD/C (N = 40) | Controls (N = 31) |
P-Valuec | |
|---|---|---|---|---|
| Subtricuspid Region | ||||
| MEDIS | −-28.4 ± 14.8a | −31.6 ± 10.4a | −38.1 ± 8.1 | 0.007 |
| TOMTEC | −24.7 ± 18.3a | −32.4 ± 12.6 | −34.3 ± 11.4 | 0.045 |
| MTT | −24.4 ± 10.8ab | −33.4 ± 10.9 | −36.9 ± 10.5 | <0.001 |
| CIRCLE | −23.0 ± 8.4a | −26.2 ± 6.3 | −27.0 ± 5.0 | 0.067 |
| Anterior Wall Region | ||||
| MEDIS | −20.6 ± 10.5ab | −28.6 ± 10.3 | −29.0 ± 11.1 | 0.001 |
| TOMTEC | −17.5 ± 11.9 | −19.7 ± 11.1 | −22.6 ± 12.5 | 0.248 |
| MTT | −17.7 ± 6.4 ab | −23.0 ± 6.1 | −22.8 ± 6.3 | 0.001 |
| CIRCLE | −22.8 ± 6.2 | −24.2 ± 5.0 | −25.3 ± 3.4 | 0.168 |
| Apical Region | ||||
| MEDIS | −22.8 ± 10.0b | −27.8 ± 8.7 | −25.1 ± 9.6 | 0.072 |
| TOMTEC | −12.7 ± 10.7 | −14.7 ± 10.4 | −13.1 ± 8.6 | 0.674 |
| MTT | −18.6 ± 8.8ab | −23.3 ± 7.8 | −25.5 ± 9.6 | 0.019 |
| CIRCLE | −18.3 ± 5.4 | −19.9 ± 5.1 | −19.5 ± 5.6 | 0.521 |
a Statistical significant difference compared to control subjects; b Statistical significant difference compared to preclinical subjects; c Trend between overt ARVD/C patients, preclinical ARVD/C and control subjects (OneWay ANOVA). Abbreviations: ARVD/C = Arrhythmogenic Right Ventricular Dysplasia/ Cardiomyopathy; MTT = Multimodality Tissue Tracking; N = number of subjects
dSegments included based on adequate tracking quality: 365/438, 429/468, and 328/360 segments in overt ARVD/C, preclinical ARVD/C and control subjects respectively