Figure 1.

Psychological effects of psilocybin. (A) Scores of the Altered States of Consciousness Rating Scale (5D-ASC) scales (n=32). Psilocybin significantly increased all scale scores compared with placebo (all P<.05), except for anxiety (P>.8). (B) Scores of the Positive and Negative Affect Schedule (PANAS) (n=31). Mood states compared from pre to post (360 minutes after drug intake). Psilocybin significantly increased positive mood (P<.05) but not negative mood (P>.8), whereas placebo had no effects on the mood scales (all P>.2). Data are expressed as mean ± SEM. *P<.05, **P<.0001.