Table 1.
Characteristics of women younger than 55 years in cohorts included in the Premenopausal Breast Cancer Collaborative Group.
| Cohort | Location | Ages at enrollment. Mean (SD), range | Calendar years of enrollment | Baseline data collection methods | N of data collection rounds* | Breast cancer cases N | Breast cancer ascertainment sources | Cohort size (women <55 years) | N years of follow-up, mean (SD), range (<55 years) |
|---|---|---|---|---|---|---|---|---|---|
| Black Women’s Health Study (10) | United States | 37.1(8.6) 20–54 |
1995 | Mailed questionnaire | 9 | 1,299 | Self-report and state registry | 52,543 | 12.6 (5.6) 0–18.6 |
| California Teachers Cohort (28) | United States | 40.4(7.4) 22–54 |
1995–1998 | Mailed questionnaire | 4 | 1,185 | State registry | 47,516 | 11.6 (5.0) 0.0–17.2 |
| Campaign against Cancer and Heart Disease (CLUE II) (13) | United States | 39.6 (9.6) 18–54 |
1989 | Administered questionnaire | 6 | 131 | State registry | 5,671 | 10.8 (5.4) 0.3–26.0 |
| Canadian Study of Diet, Lifestyle, and Health (12) † | Canada | 44.1 (6.9) 23–54 |
1991–1999 | Mailed questionnaire | 1 | 377 | Provincial and national registry | 1,589 | 8.1(4.7) 0–18.6 |
| European Prospective Investigation into Cancer and Nutrition (14) ‡ | Europe | 44.2 (8.1) 19–54 |
1991–2000 | Self-reported / administered questionnaires | 1 | 2,122 | Self-report and national/regional registries | 150,291 | 7.5 (4.2) 0–16.6 |
| Etude Epidémiologique auprès de femmes de la Mutuelle Générale de l’Education Nationale (E3N) (15) | France | 46.5 (4.2) 38–54 |
1989–1991 | Mailed questionnaire | 8 | 1,908 | Self-report | 72,748 | 8.1 (4.2) 0–16.4 |
| Generations Study (11) | United Kingdom | 39.8 (9.5) 16–54 |
2003–2012 | Mailed questionnaire | 2 | 719 | Self-report and national registry | 72,058 | 5.4 (1.7) 0–9.7 |
| Helseundersøkelsen i Nord-Trøndelag (HUNT2)(26) | Norway | 38.9 (9.7) 20–54 |
1995–1997 | Administered questionnaire | 1 | 209 | National cancer registry | 20,974 | 10.2 (4.1) 0.3–14.0 |
| Melbourne Collaborative Cohort Study (16) | Australia | 47.5 (4.4) 31–54 |
1990–1994 | Administered questionnaire | 3 | 227 | State registry | 12,029 | 7.3 (4.4) 0–20.1 |
| New York University Women’s Health Study (19, 20) | United States | 45.2(5.5) 31–54 |
1984–1991 | Self-administered questionnaire | 6 | 371 | Self-report and state registry | 8,757 | 9.5 (5.5) 0–23.5 |
| Norwegian Women and Cancer Study (105) | Norway | 45.7 (6.0) 31–54 |
1991–2007 | Mailed questionnaire | 3 | 2,124 | National registry | 117,633 | 9.0 (5.8) 0.3–20.5 |
| Nurses’ Health Study (17) | United States | 42.6 (7.1) 29–54 |
1976–1978 | Mailed questionnaire | 16 | 2,743 | Self-report | 117,730 | 12.2 (7.0) 0.1–25.5 |
| Nurses’ Health Study II (18) | United States | 34.8 (4.7) 24–44 |
1989–1990 | Mailed questionnaire | 12 | 3,765 | Self-report | 116,415 | 18.7 (3.7) 0.1–23.7 |
| Radiation Effects Research Foundation Life Span Study (21) | Japan | 41.3 (8.5) 18–54 |
1963–1993 | Administered or mailed questionnaire | 6 | 130 | City registry | 18,420 | 13.5 (8.5) 0.1–36.7 |
| Singapore Chinese Health Study (22) | Singapore | 49.6 (3.0) 43–54 |
1993–1998 | Administered questionnaire | 2 | 134 | National cancer registry | 16,056 | 5.3 (3.0) 0.3–11.5 |
| Sister Study (6) | United States | 47.9 (4.9) 35–54 |
2003–2009 | Telephone and written questionnaire | 3 | 679 | Self-report | 24,044 | 4.7 (2.5) 0.1–10.6 |
| Southern Community Cohort Study (23) | United States | 47.3 (4.2) 40–54 |
2002–2009 | Administered questionnaire | 2 | 233 | State registry | 30,289 | 5.1 (2.4) 0.1–13.3 |
| Sweden Women’s Lifestyle and Health Study (27) | Sweden | 39.7 (5.8) 29–49 |
1991–1992 | Mailed questionnaire | 2 | 1,192 | National registry | 49,010 | 14.4 (5.3) 0.1–21.1 |
| Swedish Mammography Cohort (24) | Sweden | 46.6 (4.3) 38–54 |
1987–1990 | Mailed questionnaire | 2 | 649 | National registry | 34,126 | 8.3 (4.3) 0–16.6 |
| United States Radiologic Technologist Cohort (25) | United States | 36.8 (7.3) 22–54 |
1983–1998 | Mailed questionnaire | 3 | 1,570 | Self-report | 62,862 | 14.5 (5.6) 0–22.8 |
*
contributed as of June 2016, includes baseline and each follow-up.
†
The Canadian Study of Diet, Lifestyle, and Health is the only case-cohort study. The cohort size (N=1,589) represents the subcohort only.
‡
The European Prospective Study into Cancer and Nutrition (EPIC) dataset does not include the French or Norwegian EPIC sites which contributed from the Etude Epidémiologique auprès de femmes de la Mutuelle Générale de l’Education Nationale and Norwegian Women and Cancer Study directly.