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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Clin Cancer Res. 2017 Jun 9;23(17):5281–5291. doi: 10.1158/1078-0432.CCR-17-0171

Figure 5.

Figure 5

miR-193a-3p decreases cellular proliferation and targets IL-17RD. A) Cellular proliferation at 48 hours in the indicated cell lines following transfection with 25 nM of miR-193a-3p or scrambled control. B) Activity of luciferase regulated by mutated or wild type IL17RD 3’-UTR following transfection with mature miR-193a-3p or a scrambled control oligonucleotide. Results are expressed as the ratio of firefly to renilla luciferase activity and normalized to empty vector. C). Expression of IL17RD by Western blot following transfection with 6.25 nM or 12.5 nM of miR-193a-3p in HUVEC cells. D) RNA transcript expression of IL17RD following transfection of 6.25 nM or 12.5 nM of IL17RD in HUVEC or HCT116 cells.