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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Clin Cancer Res. 2017 Jun 19;23(17):5055–5065. doi: 10.1158/1078-0432.CCR-16-2946

Figure 1. Radiation increases expression of tumor-associated antigens and immune recognition by antigen-specific T cells.

Figure 1

A498 cells were treated or untreated with radiation. Immunomodulatory markers (A) and tumor-associated antigens (B) were measured at indicated times by flow cytometry. Data (mean ± s.e.m.) are from ≥ 3 independent experiments. (C) 96 h after treatment, A498 tumor cells were cocultured with expanded NY-ESO-1 specific CD8 T cells and monitored for IFN-ɣ secretion by ELISPOT assays. One representative experiment out of two is shown (mean ± s.e.m.). *P < 0.05 vs. 0 Gy; unpaired two-tailed Student’s t-test.