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. Author manuscript; available in PMC: 2018 Sep 1.
Published in final edited form as: Mol Cancer Res. 2017 May 26;15(9):1197–1205. doi: 10.1158/1541-7786.MCR-17-0095

Figure 1. Properties of circulating microDNA from mouse serum are similar to those observed in mouse tissues.

Figure 1

(A) Length distribution of microDNAs identified in the serum of two mice. (B) Median percent GC content of microDNAs and the genomic sequences of equal length upstream or downstream of the microDNA source loci are enriched relative to the average GC content of the mouse genome (dashed line). (C) Distribution of microDNA in the indicated genomic regions. (D) Percentage of microDNA with (black) or without (gray) 2- to 15-bp direct repeats flanking the microDNA locus at the genomic source.