Table 1.
Socio-demographics of Adults with Down syndrome at Cycle 1 and Cycle 2
| Cycle 1 | Cycle 2 | |||||
|---|---|---|---|---|---|---|
|
| ||||||
| Total N = 58* |
PiB− N = 39 |
PiB+ N = 17 |
Total N = 58* |
PiB− N = 32 |
PiB+ N = 22 |
|
| Sex | ||||||
| Male n (%) | 30(51.7) | 17(43.6) | 11(64.7) | 30(51.7) | 16(50.0) | 11(50.0) |
| Age in years, M (SD) | 37.6(6.8) | 34.6(5.4) | 44.6(4.2) | 40.5(7.1) | 36.4(5.4) | 45.9(4.8) |
| Race/Ethnicity, n (%) | ||||||
| White | 57(98.3) | 39(100) | 16(94.1) | 56(98.2) | 32(100) | 20(95.2) |
| American Indian/Alaska Native | 1(1.7) | 0(0) | 1(5.9) | 1(1.7) | 0(0) | 1(4.8) |
| Residence, n (%) | ||||||
| Family | 37 (63.8) | 25(64.1) | 10(58.8) | 36(62.1) | 19(59.4) | 14 (63.6) |
| Group home | 7 (12.1) | 3(7.7) | 4(23.5) | 6(10.3) | 2(6.3) | 4(18.2) |
| Supported apartment | 9(15.5) | 7(17.9) | 2(11.8) | 8(13.8) | 6(18.8) | 2(9.1) |
| Independently | 4(6.9) | 3(7.7) | 1(5.9) | 5(8.6) | 4(12.5) | 0(0) |
| Other | 1 (1.7) | 1(2.6) | 0(0) | 3(5.2) | 1(3.1) | 2(9.1) |
| Employment, n (%) | ||||||
| Full or part time | 19(32.8) | 13(33.3) | 5(29.4) | 20(34.5) | 10(31.3) | 9(40.9) |
| Full or part time with support | 13(22.4) | 10(25.6) | 3(17.6) | 11(19.0) | 9(28.1) | 1(4.5) |
| Supported workshop | 14(24.1) | 8(20.5) | 5(29.4) | 13(22.4) | 7(21.9) | 4(18.2) |
| Volunteer | 6(10.3) | 3 (7.7) | 3(17.6) | 5(8.6) | 2(6.3) | 3(13.6) |
| Day treatment or not employed | 6(10.3) | 5(12.8) | 1 (5.9) | 9(15.5) | 4(12.5) | 5(22.7) |
| Mental Age in years, M (SD) | 5.5 (1.3) | 5.6(1.1) | 5.5(1.6) | 5.8(2.7) | 6.4(3.3) | 5.1(1.4) |
| Dementia Symptoms | ||||||
| DSDS - CCS, n (%) 3 or above | 2(3.4%) | 1(2.6%) | 1(5.9%) | 5(8.6)* | 1(3.1) | 3(13.6) |
| Medications | ||||||
| Hypothyroidism | 31(53.4) | 23(59.0) | 7(41.2) | 36(63.2) | 22(71.0) | 11(50.0) |
| Hypertension | 3(5.2) | 2(5.1) | 1(5.9) | 4(6.9) | 2(6.3) | 2(9.1) |
| Antipsychotic | 7(12.1) | 3(7.7) | 4(23.5) | 6(10.3) | 2(6.3) | 4(18.2) |
| Antidepressant/anti-anxiety | 16 (27.6) | 11(28.2) | 5(29.4) | 18(31.0) | 8(25.0) | 9(40.9) |
| Mood/Behavior stabilizer | 1 (1.7) | 0(0) | 1(5.9) | 2(3.4) | 0(0.0) | 2(9.1) |
| Narcotic Pain reliever | 1 (1.7) | 0(0) | 1(5.9) | 2(3.4) | 1(3.1) | 1(4.5) |
| Cholesterol | 7(12.1) | 3(7.7) | 3(17.6) | 8(13.8) | 2(6.3) | 4(18.2) |
| Memory enhancer/Alzheimer’s | 0(0) | 0(0) | 0(0) | 0(0) | 0(0) | 0(0) |
| Other | 0(0) | 0(0) | 0(0) | 0(0) | 0(0) | 0(0) |
Note.
*
Total number does not equal sum of PiB- and PiB+ given that PiB status could only be determined on 56 participants at Cycle 1 and 54 participants at Cycle 2. Mental age was assessed using the Stanford-Binet, Fifth Edition Abbreviated Battery (Roid, 2003), DSDS-CCS = Down Syndrome Dementia Scale (Gedye, 1995) – Cognitive Cutoff.