Figure 7.
Reduced markers of inflammation after oral delivery of Salmonella enterica Typhimurium strain SL1344 (St) in the presence of antibody preparations. (A) Frequency of neutrophils and macrophages was determined as a function of the total number of cells in PPs, 6 days post-administration of 2 × 107 St alone or in association with 1 mg of IgA/M or SCIgA/M preparations. (B) Pro-inflammatory cytokine secretion measured in cell culture suspensions of PPs from the same experimental groups as in (A). Experiments were performed twice, with three mice per group, and the compilation of the two experimental sets is depicted. Bars represent medians. Statistical analyses were performed by comparison with the “No Ab” experimental group. Ab, antibody.