Table 3.

Principal component analysis (PCA) synthesis: qualitative analysis of PCA group separation for global PCA and focused PCA.

	PCA
	P25		P45		P95
	Global PCA	Focused PCA	Global PCA	Focused PCA	Global PCA	Focused PCA
Nucleus accumbens	−	Dopamine++	−	−	+++	γ-Aminobutyric acid (GABA)+++, epigenetic+, plasticity+
Ventral tegmental area	−	−	−	−	++	Epigenetic++, plasticity+
Hypothalamus	−	Plasticity++	−	−	−	GABA+++, plasticity+

A qualitative scale was used for the analysis of the PCA and focused PCA: +++: very good separation; ++: good separation with one rat on the wrong side of the PCA separation; +: quite good separation with two rats (one of each group) on the wrong side, −: no clear separation.