Table 2.
Baseline parameters of transcranial magnetic stimulation (TMS) in the three groups.
| RMT (%MSO) | AMT (%MSO) | MEP1mVa (%MSO) | Inion AMT (%MSO) | Conditional TMS intensity for SICI (%MSO) | Baseline SICIb(%) | Conditional TMS intensity for ICF (%MSO) | Baseline ICFb (%) | Conditional TMS intensity for CBI (%MSO) | Baseline CBIb (%) | |
|---|---|---|---|---|---|---|---|---|---|---|
| HC | 51.6 ± 7.9 | 47.3 ± 8.1 | 67.0 ± 12.4 | 44.1 ± 4.5 | 40.0 ± 5.5 | 45.9 ± 22.9§ | 40.0 ± 5.5 | 148.7 ± 32.7 | 41.9 ± 4.3 | 84.7 ± 15.1§ |
| PD | 48.6 ± 10.4 | 44.6 ± 9.3 | 65.1 ± 15.6 | 42.1 ± 4.5 | 40.2 ± 8.7 | 62.4 ± 30.7 | 39.7 ± 9.5 | 147.9 ± 41.2 | 40.0 ± 4.3 | 91.9 ± 21.6 |
| SCA3 | 50.9 ± 7.6 | 47.1 ± 7.2 | 61.1 ± 13.7 | 44.1 ± 5.1 | 42.3 ± 7.5 | 79.1 ± 41.1§ | 42.3 ± 7.7 | 146.3 ± 62.7 | 41.9 ± 4.9 | 101.9 ± 17.2§ |
Data are presented as mean ± SD.
aThe intensity of TMS producing motor-evoked potentials (MEPs) of on average 1 mV in peak-to-peak amplitude in the resting first dorsal interosseus.
bData shown by the mean conditioned MEP amplitude as a percentage of the unconditioned mean.
§P < 0.05 by non-parametric Mann–Whitney U test with Bonferroni’s correction.
AMT, active motor threshold; CBI, cerebellar inhibition; HC, health control; ICF, intracortical facilitation; MSO, maximum stimulator output; PD, Parkinson’s disease; RMT, resting motor threshold; SCA3, spinocerebellar ataxia type 3; SICI, short-interval intracortical inhibition.