Table 4.
Evaluation of a class solution for prostate IMRT. Percentage volumes associated with organs at risk (mean [SD] or median [range]): comparison of the clinical plan (CP) and class solutions T1, T2 and Tfinal.
| Metric | CP | T1 | T2 | Tfinal | RM-ANOVA (P value) |
|---|---|---|---|---|---|
| [RECTUM] volume (cc) covered by 102.5%TD | 0.344 (0.000–1.915) | 0.115***,††† (0.000–0.439) | 0.424†† (0.000–2.238) | 0.194 (0.000–1.776) | <0.0001 |
| [RECTUM] % covered by 40 Gy | 29.26 (7.95) | 30.19 (9.50)***,††† | 29.41 (9.19) | 29.78 (9.24) | <0.0001 |
| [RECTUM] % covered by 65 Gy | 11.22 (5.21) | 10.57 (5.47)**,† | 11.02 (5.80) | 11.15 (5.69) | 0.0118 |
| [RECTUM] % covered by 75 Gy | 6.50 (3.60) | 5.65 (3.65)***,††† | 6.50 (4.22) | 6.36 (3.98) | <0.0001 |
| [BLADDER] % covered by 60 Gy | 13.23 (7.76) | 16.20***,††† (9.85) | 12.67 (7.71) | 13.07 (8.05) | <0.0001 |
| [BLADDER] % covered by 40 Gy | 22.97 (13.88) | 26.28***,††† (15.82) | 22.23 (13.60) | 22.53 (13.96) | <0.0001 |
| [BULB] % covered by 50 Gy | 0.000 (0.000–40.23) | 0.000 (0.000–45.12) | 0.000 (0.000–50.52) | 0.000 (0.000–35.98) | 0.0697 |
| [L FEMORAL HEAD] % covered by 45 Gy | 0.000 (0.000–1.328) | 0.000***,††† (0.000–3.834) | 0.000* (0.000–0.299) | 0.000** (0.000–0.300) | 0.0236 |
| [R FEMORAL HEAD] % covered by 45 Gy | 0.000 (0.000–1.861) | 0.000 ***,††† (0.000–4.438) | 0.000 (0.000–0.461) | 0.000 (0.000–0.443) | 0.0004 |
*
Compared to CP, P < 0.05.
**
P < 0.01.
***
P < 0.0001.
†
Compared to Tfinal, P < 0.05.
††
P < 0.01.
†††
P < 0.0001.