Table 3.
Subthreshold Psychotic Symptoms Across the Life Span in 22q11.2 Deletion Syndrome Participants Without Psychotic Disorder
| Definitions | No. (%)a | ||||||
|---|---|---|---|---|---|---|---|
| Children (n = 184) | Adolescents (n = 276) | Young Adults (n = 231) | Older Adults (n = 67) | χ2 | P | ES | |
| Positive subthreshold symptoms | 48/175 (27.4) | 97/251 (38.5) | 69/203 (33.9) | 13/55 (23.6) | 8.31 | .04 | .11 |
| Negative/disorganized subthreshold symptoms | 34/126 (27.0) | 55/142 (38.7) | 40/143 (28.0) | 11/47 (23.4) | 6.81 | .08 | .12 |
| Positive + negative/disorganized subthreshold symptoms | 31/123 (25.2) | 69/156 (44.2) | 52/155 (33.5) | 8/44 (18.2) | 16.50 | <.001 | .19 |
| Acute positive subthreshold symptoms | 1/175 (<0.5) | 5/159 (3.1) | 0/134 (0) | 0/42 (0) | 6.82 | .08 | .12 |
Note: ES, effect size Eta-squared (η2).
a
% of valid cases (participants for whom the SIPS negative/disorganized symptoms were missing were withdrawn from the relevant analysis; n = 67); Statistical analysis conducted with chi-square tests (χ2); Children, aged 6–12 years, mean age 10.3 ± 1.4; Adolescents, 13–17 years, 14.9 ± 1.4; Young adults, 18–25 years, 20.7 ± 2.2; Older adults, 26 years and above, mean age 33.0 ± 6.5; Male/female ratio did not differ between the 4 age groups, χ2(3) = 4.94, P = .18.