Table 3.

Body and plantaris muscle weight in Study 1

	Sham	Sham + EMIQ	Ovld	Ovld + EMIQ		P value
					Ovld	EMIQ	Ovld × EMIQ
Food intake (g day−1)	5.1 ± 0.2	5.2 ± 0.2	5.0 ± 0.2	5.0 ± 0.2	0.388	0.711	0.849
Initial body weight (g)	35.9 ± 0.5	35.5 ± 0.7	36.0 ± 0.5	35.0 ± 0.6	0.749	0.222	0.609
Final body weight (g)	39.3a ± 0.6	39.7a ± 0.7	38.1b ± 0.9	37.6b ± 0.6	0.032	0.964	0.547
Left Plantaris (mg)	21.6a ± 1.0	22.7a ± 0.9	43.4b ± 2.3	46.0b ± 3.2	0.000	0.388	0.727
Right Plantaris (mg)	21.8a ± 0.9	23.3a ± 0.8	41.5b ± 3.0	45.3b ± 3.7	0.000	0.298	0.638
Av. Plantaris (mg)	21.7a ± 0.6	23.0a ± 0.8	42.4b ± 2.3	45.6b ± 3.2	0.000	0.290	0.648
Plantaris/B.W. (%)	0.055a ± 0.002	0.058a ± 0.002	0.111b ± 0.005	0.121b ± 0.007	0.000	0.290	0.648

Values are mean ± SEM. Means without a common letter are statistically different (P < 0.05, two-way ANOVA (analysis of variance) followed by Tukey’s test). Sham: sham-operated mice, Sham + EMIQ: sham-operated mice receiving EMIQ, Ovld: functionally overloaded mice, Ovld + EMIQ: functionally overloaded mice receiving EMIQ