Table 4.
Effect of age at first day care during the first year of life for acute lymphoblastic leukaemia (ALL) and non-ALL malignancies
|
Day care
|
Formal day care
|
|||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Age first attended (months)
|
No (%)
|
Odds ratio*(95%Cl)
|
No (%)
|
Odds ratio*(95%Cl)
|
||||||||
| Controls (n=6250)† | ALL (n=1274)† | Non-ALL (n=1830)† | ALL v controls | Non-ALL v controls | ALL v non-ALL | Controls (n=6269)† | ALL (n=1278)† | Non-ALL (n=1833)† | ALL v controls | Non-ALL v controls | ALL v non-ALL | |
| None | 3736 (59.8) | 839 (65.9) | 1210 (66.1) | 1.00 | 1.00 | 1.00 | 5534 (88.3) | 1170 (91.5) | 1652 (90.1) | 1.00 | 1.00 | 1.00 |
| <3 | 1091 (17.5) | 185 (14.5) | 289 (15.8) | 0.71 (0.60 to 0.85) | 0.88 (0.76 to 1.02) | 0.82 (0.66 to 1.02) | 231 (3.7) | 27 (2.1) | 71 (3.9) | 0.56 (0.37 to 0.83) | 1.07 (0.81 to 1.40) | 0.52 (0.32 to 0.83) |
| 3-5 | 548 (8.8) | 94 (7.4) | 130 (7.1) | 0.71 (0.56 to 0.90) | 0.83 (0.68 to 1.02) | 0.91 (0.68 to 1.22) | 204 (3.3) | 35 (2.7) | 42 (2.3) | 0.71 (0.49 to 1.03) | 0.77 (0.55 to 1.08) | 1.01 (0.62 to 1.64) |
| 6-11 | 875 (14.0) | 156 (12.2) | 201 (11.0) | 0.76 (0.63 to 0.92) | 0.76 (0.64 to 0.91) | 1.00 (0.79 to 1.27) | 300 (4.8) | 46 (3.6) | 68 (3.7) | 0.69 (0.50 to 0.96) | 0.82 (0.62 to 1.08) | 0.81 (0.54 to 1.21) |
*
Odds ratio for cases compared with all controls or with non-ALL malignancies where stated, adjusted for age at diagnosis or pseudodiagnosis, sex, region, maternal age, mother working at time of birth, and deprivation.
†
Excluding missing values.