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. Author manuscript; available in PMC: 2018 Oct 1.
Published in final edited form as: Eur J Pharm Biopharm. 2017 Jun 6;119:81–90. doi: 10.1016/j.ejpb.2017.06.004

Table 1.

HME formulations

Experiment Number Formulation (%w/w) Temperature (°C) Sucralose Magnasweet Citric acid CPM GLY Lycoat 780 Screw speed (rpm)
1 N 1 100 0.5 0.5 4 5 20 70 50
2 N 2 110 0.5 0.5 4 5 17 73 30
3 N 3 100 0.5 0.5 6 5 17 71 50
4 N 4 110 0.5 0.5 6 5 20 68 30
5 N 5 100 0.5 0.5 4 10 20 65 30
6 N 6 110 0.5 0.5 4 10 17 68 50
7 N 7 100 0.5 0.5 6 10 17 66 30
8 N 8 110 0.5 0.5 6 10 20 63 50
9 N 9 105 0.5 0.5 5 7.5 18.5 68 40