. Author manuscript; available in PMC: 2018 Oct 1.

Published in final edited form as: J Mech Behav Biomed Mater. 2017 May 31;74:118–127. doi: 10.1016/j.jmbbm.2017.05.039

Table 1.

Comparison of AFM studies on mechanical properties of lung vascular tissue.

Lung Tissue Sample	Tissue Thickness	Tip Radius and Geometry	Young’s Modulus E (kPa)	References
Normal Lung Tissue
*Mice*
Pulmonary vessel	250 μm	40 nm - pyramidal	3.293 ± 1.177 ^#	Meng et al., 2015
*Rat*
Pulmonary artery	50 μm	2.5 μm - spherical	1.66 ± 0.49 ^# ^&	Liu et al., 2016
*Human*
Pulmonary artery	10 μm	2.5 μm - spherical	5.44 ± 2.96 ^# ^&	Liu et al., 2016
Decellularized Lung Tissue
*Mice*
Tunica intima	10 μm	20 nm - pyramidal	79.3 ± 7.2 ^*	Melo et al., 2014a
Tunica adventitia	10 μm	20 nm - pyramidal	41.1 ± 8.0 ^*	Melo et al., 2014a

Mean ± standard deviation (SD)

Mean ± standard error (SE)

Young’s modulus E was calculated from shear modulus G values using the relationship E = 2 × (1 + ν) × G (from Liu et al., 2010)