Table 1.
Characteristic | Study participants (N=220) |
||
---|---|---|---|
n | % | ||
Gender | Female | 124 | 56 |
Age distribution (years) | 12 to <18 | 42 | 19 |
18 to <30 | 116 | 53 | |
≥30 | 62 | 28 | |
Race | White | 198 | 90 |
Hispanic | 12 | 5 | |
Unknown/Other | 10 | 5 | |
Genotype | Homozygous F508del | 121 | 55 |
Heterozygous F508del | 82 | 37 | |
Other | 16 | 7 | |
Not available | 1 | 1 | |
Insurance status* | Enrolled in Medicaid | 76 | 37 |
Pancreatic status* | Prescribed pancreatic enzymes | 196 | 89 |
FEV1 % predicted* | <40 | 74 | 36 |
40–<70 | 84 | 41 | |
70–<100 | 42 | 21 | |
≥100 | 3 | 1 | |
Respiratory microbiology*†‡ | Pseudomonas aeruginosa | 154 | 71 |
Mucoid P. aeruginosa | 121 | 56 | |
Staphylococcus aureus (methicillin susceptible) | 78 | 36 | |
Methicillin-resistant S. aureus | 84 | 39 | |
Stenotrophomonas maltophilia | 31 | 14 | |
Achromobacter xylosoxidans | 20 | 9 | |
Burkholderia cepacia complex | 6 | 3 | |
Aspergillus spp. | 47 | 22 | |
Non-tuberculous Mycobacteria (NTM)* | Yes | 16 | 7 |
Allergic bronchopulmonary aspergillosis (ABPA)* | Yes | 28 | 13 |
CF-related diabetes mellitus* | Yes | 86 | 39 |
Chronic CF medications*†‡ | Inhaled tobramycin | 155 | 71 |
Inhaled aztreonam | 111 | 51 | |
Inhaled colistimethate | 30 | 14 | |
Dornase alfa | 207 | 95 | |
Hypertonic saline | 170 | 78 | |
Azithromycin | 164 | 75 | |
Ivacaftor | 8 | 4 |
Excludes missing data for insurance status (n = 14), pancreatic status (n = 1), FEV1 % predicted (n = 17), respiratory microbiology (n = 4), non-tuberculous Mycobacteria (n = 2), ABPA (n = 1), CF-related diabetes mellitus (n = 1), chronic CF medications (n = 1)
Includes respiratory cultures recorded up to 6 months prior to admission and chronic medications recorded up to 12 months prior
Categories are not mutually exclusive and may add up to >100%