Table 2.
Association of Floor Maze test performance (immediate maze time and delayed maze time) with incidence of mild cognitive impairment syndrome (MCI), motoric cognitive risk syndrome (MCR) and major cognitive impairment (either MCI or MCR). Hazard ratios are reported for each 10-second increase in IMT, DMT and Maze time difference.
Incident cases, n | Adjusted Hazard Ratio (95% CI), p-value* | |
---|---|---|
Immediate Maze Time | ||
MCI | 41 | 1.254 (1.063–1.480), p = 0.007 |
Amnestic MCI | 19 | 0.991 (0.769–1.277), p = 0.944 |
Non-amnestic MCI | 22 | 1.198 (1.067–1.345), p = 0.002 |
MCR | 30 | 1.530 (1.230–1.903), p < 0.001 |
Major Cognitive Impairment | 55 | 1.264 (1.069–1.494), p = 0.006 |
Delayed Maze time | ||
MCI | 41 | 1.187 (0.897–1.571), p = 0.230 |
Amnestic MCI | 19 | 0.847 (0.460–1.559), p = 0.593 |
Non-amnestic MCI | 22 | 1.137 (0.867–1.492), p = 0.354 |
MCR | 30 | 1.321 (1.031–1.693), p = 0.028 |
Major Cognitive Impairment | 55 | 1.493 (1.119–1.993), p = 0.006 |
Maze time difference (DMT-IMT)** | ||
MCI | 41 | 0.760 (0.615–0.939), p = 0.011 |
Amnestic MCI | 19 | 0.987 (0.705–1.381), p = 0.937 |
Non-amnestic MCI | 22 | 0.805 (0.688–0.942), p = 0.007 |
MCR | 30 | 0.763 (0.593–0.981), p = 0.035 |
Major Cognitive Impairment | 55 | 0.864 (0.691–1.080), p = 0.199 |
Adjusted for age, sex, education, Blessed test score, Global Health Scale score, and maze errors
Maze time difference is the difference between DMT and IMT in each participant, and is a measure of learning.