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. 2017 Aug 30;11:59. doi: 10.3389/fncir.2017.00059

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Copyright © 2017 Noga, Turkson, Xie, Taberner, Pinzon and Hentall.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Change in monoaminergic extracellular concentration during MLR-evoked fictive locomotion. (A) Peak NE and 5-HT release during MLR-evoked fictive locomotion in DH, IZ/VH and adjacent WM (mean ± SEM). Note that NE release was significantly greater than 5-HT in the gray matter. (B) Comparison of peak monoamine concentrations observed with MLR evoked locomotion (loco) vs. no locomotion (bursting) in DH, IZ/VH and adjacent WM. Note that in the DH and IZ/VH, a significantly greater release of NE over baseline was observed in trials with locomotor activity. (C,D) Release of NE and 5-HT within the IZ/VH was significantly correlated to the time required to elicit locomotion with MLR stimulation. *p < 0.05, **p < 0.01.