Table 4.
Simulated lifetime effects of low dose aspirin compared with no aspirin on cohorts of 10 000 men and 10 000 women in Australia, initially aged 70-74 years and free from cardiovascular disease. Figures are point estimates with 95% uncertainty intervals
| Lifetime effects (≥70) | Men | Women |
|---|---|---|
| Cases prevented: | ||
| Coronary heart disease | 389 (213 to 581) | 321 (170 to 484) |
| Ischaemic stroke | 19 (−107 to 146) | 35 (−99 to 168) |
| Haemorrhagic stroke | −76 (−195 to 28) | −54 (−136 to 22) |
| Major gastrointestinal haemorrhage | −499 (−740 to −266) | −572 (−849 to −308) |
| Deaths prevented: | ||
| Coronary heart disease | 186 (92 to 287) | 153 (73 to 241) |
| Ischaemic stroke | −14 (−94 to 64) | 7 (−69 to 83) |
| Haemorrhagic stroke | −62 (−163 to 23) | −44 (−121 to 20) |
| Major gastrointestinal haemorrhage | −89 (−133 to −48) | −70 (−105 to −38) |
| Other causes | −17 (−139 to 108) | −40 (−154 to 72) |
| Total deaths | 3 (−9 to 16) | 6 (−8 to 20) |
| Years of life saved | 20 (−784 to 774) | 145 (−496 to 780) |
| Health adjusted years of life saved | 3 (−654 to 623) | 106 (−488 to 678) |