Figure 2.

Octopus bimaculoides editing sites were distinguished based on whether they are found only in O. bimaculoides (‘unique’), shared with the congener O. vulgaris but not with other cephalopods (‘octopus’), shared with the squid Doryteuthis pealeii but not with all sampled cephalopods (‘oct-squid’), or shared with all sampled cephalopods (‘cephalopods’) [14]. (a) The proportion of edits that restore the ancestral protein sequence decreases for classes of edit sites that are more widely shared across cephalopods. (b) More widely shared sites also have a higher editing frequency (i.e. a larger percentage of transcripts are edited at that site) [14]. Within each group, however, edits that restore the ancestral amino acid have a higher average editing frequency than those that result in a derived change. Errors bars represent one standard error of the proportion (a) or of the mean (b). The number of analysed sites is indicated in parentheses.