Table 3. Univariate and multivariate Cox regression analysis of CYP4A⁺ TAM counts for recurrence-free survival of breast cancer patients in the tissue microarray.

Characteristics	Univariate analysis		Multivariate analysis
	HR (95% CI)	P-value	HR (95% CI)	P-value
Age (⩽54 vs >54)	1.107 (0.586–2.092)	0.753
Pathological grade (I–II vs III)	2.278 (1.201–4.322)	0.012*	1.561 (0.747–3.263)	0.237
T stage (T1 vs T2–T3)	0.936 (0.492–1.783)	0.841
ER (negative vs positive)	0.407 (0.215–0.770)	0.006*	0.371 (0.180–0.767)	0.007*
PR (negative vs positive)	1.124 (0.593–2.131)	0.720
Her-2 (negative vs positive)	0.955 (0.483–1.891)	0.895
Lymph node metastasis (0 vs ⩾1)	2.963 (1.494–5.879)	0.002*	2.587 (1.276–5.248)	0.008*
TNM stage (I vs II–III)	2.333 (0.911–5.978)	0.078
CYP4A+ TAM counts (low vs high)	2.367 (1.210–4.632)	0.012*	2.221 (1.041–4.735)	0.039*

Abbreviations: CI, confidence interval; ER, estrogen receptor; Her-2, human epidermal growth factor receptor-2; HR, hazard ratio; PR, progesterone receptor; TNM, tumor node metastasis.

*P <0.05.