Table 1.
Effects of fructose feeding on metabolic parameters
| C | FF | P value | |
|---|---|---|---|
| Plasma fasting glucose (mg dL−1) | 95 (78; 97) | 124 (123; 136) | 0.008 |
| Plasma fasting insulin (ng mL−1) | 1.066 ± 0.21 | 2.69 ± 0.17 | 0.0003 |
| QUICKI | 0.295 ± 0.007 | 0.250 ± 0.002 | 0.0004 |
| Plasma triglycerides (mg mL−1) | 62 (58; 90) | 341 (279; 487) | <0.001 |
| GTT‐AUC (mmol L−1 min−1) | 1053 ± 63 | 1569 ± 40 | 0.0001 |
| IST‐AUC (mmol L−1 min−1) | 452 (439; 457) | 717 (686; 802) | 0.008 |
Data are presented as mean ± SE or median (25th; 75th percentile). n = 5 (all parameters, except plasma triglycerides), n = 10 (triglycerides). Bold indicates the results significant at the 0.05 level.
C, age‐matched control rats (fed standard chow and water); FF, rats fed standard chow and 10% fructose added to the drinking water; AUC, area‐under‐the‐curve; GTT, glucose tolerance test; IST, insulin sensitivity test; QUICKI, quantitative insulin sensitivity check index.